The Big 12 doesn't often get the same spotlight as the SEC and Big Ten, especially, but it provides perhaps the top matchup in Week 11 of college football. No. 8 BYU takes on No. 9 Texas Tech in a battle of teams with conference championship and College Football Playoff aspirations.

College football Week 10 Big 12 picks, predictions, probabilities for Texas Tech-Kansas State, UCF-Baylor, Arizona-Colorado, Cincinnati-Utah, more.

Star sports staffers Michael Lev and Justin Spears and 2025-26 guest prognosticator Jordan Hamm make their picks for Week 10 in Big 12 play, including the Arizona-Colorado matchup

The only top-10 battle in the country will take place in Lubbock where undefeated BYU takes on its biggest test of the season against Texas Tech. This game figures to be decided in the trenches, where both teams have had the advantage on most opponents all season.

College football Week 8 score predictions, picks for every Big 12 game, including Texas Tech-Arizona State, Utah-BYU, Baylor-TCU, West Virginia-UCF.