Gut

Robot versus conventional ESD for colonic lesions: results from a randomising model trial

Endoscopic submucosal dissection (ESD) enables en bloc resection for early gastrointestinal malignancies but is technically ...
Gut

SIRT6 promotes intrahepatic cholangiocarcinoma development by reprogramming glutamine metabolism via enhanced GLUL

Background SIRT6 acts as a tumour suppressor in multiple cancers by regulating glucose and lipid metabolism, but its role in ...
Gut

Characteristics of an antibody profile associated with protection against hepatitis C virus reinfection in a high-risk cohort

Early broadly neutralising antibody responses against the E1E2 glycoprotein seem to be important for preventing persistence ...
gut.bmj

A practical guide to assess the Nancy histological index for UC

4 Inserm U954, University of Lorraine, Vandoeuvre-lès-Nancy, France Correspondence to Professor Laurent Peyrin-Biroulet, Department of Gastroenterology, Inserm U954, Université de Lorraine, Allée du ...
gut.bmj

The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications

4 Department of Hepatogastroenterology, Hopital Claude Huriez, CHRU Lille, France Correspondence to: Professor J-F Colombel Department of Hepato-Gastroenterology, Hopital Claude Huriez, CHRU de Lille, ...
gut.bmj

High risk of hepatocellular carcinoma and death in patients with immune-tolerant-phase chronic hepatitis B

Objective High serum HBV DNA levels are associated with high risks of hepatocellular carcinoma (HCC) and cirrhosis in patients with chronic hepatitis B (CHB). Although the immune-tolerant (IT) phase ...
gut.bmj

Risk assessment after acute upper gastrointestinal haemorrhage.

The aim of this study was to establish the relative importance of risk factors for mortality after acute upper gastrointestinal haemorrhage, and to formulate a simple numerical scoring system that ...
gut.bmj

Complete and incomplete intestinal metaplasia at the oesophagogastric junction: prevalences and associations with endoscopic erosive oesophagitis and gastritis

BACKGROUND/AIMS Intestinal metaplasia (IM) is a common finding at the oesophagogastric junction, but the aetiopathogenesis of the different IM subtypes—that is, incomplete IM (specialised columnar ...
gut.bmj

Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation

Section of Digestive Diseases and Nutrition, University of Illinois at Chicago and Chicago Veterans Administration Medical Center (West Side Division), Chicago, IL, USA Correspondence to: Dr G Hecht, ...
gut.bmj

Depression in individuals who subsequently develop inflammatory bowel disease: a population-based nested case–control study

Correspondence to Dr Richard C Pollok, Gastroenterology, St George's University Hospitals NHS Foundation Trust, London SW17 0QT, UK; richard.pollok{at}nhs.net Objective Depression is a potential risk ...
gut.bmj

ABC score: a new risk score that accurately predicts mortality in acute upper and lower gastrointestinal bleeding: an international multicentre study

Objectives Existing scores are not accurate at predicting mortality in upper (UGIB) and lower (LGIB) gastrointestinal bleeding. We aimed to develop and validate a new pre-endoscopy score for ...
gut.bmj

Are random biopsies still useful for the detection of neoplasia in patients with IBD undergoing surveillance colonoscopy with chromoendoscopy?

Background Colonoscopy with pan-chromoendoscopy (CE) is superior to standard colonoscopy in detecting neoplasia in patients with IBD. Performing random biopsies in unsuspicious mucosa after CE remains ...